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Kazuo Tsubota Selected Research

Ophthalmic Solutions (Eye Drops)

1/2022Adherence to Eye Drops Usage in Dry Eye Patients and Reasons for Non-Compliance: A Web-Based Survey.
5/2021Efficacy and safety of 0.01% atropine for prevention of childhood myopia in a 2-year randomized placebo-controlled study.
5/2020The Effects of High Molecular Weight Hyaluronic Acid Eye Drop Application in Environmental Dry Eye Stress Model Mice.
4/2020Author Correction: Suppression of presbyopia progression with pirenoxine eye drops: experiments on rats and non-blinded, randomized clinical trial of efficacy.
1/2020The Effects of 3% Diquafosol Sodium Eye Drops on Tear Function and the Ocular Surface of Cu, Zn-Superoxide Dismutase-1 (Sod1) Knockout Mice Treated with Antiglaucoma Eye Medications.
8/2019The Effects of Rebamipide 2% Ophthalmic Solution Application on Murine Subbasal Corneal Nerves After Environmental Dry Eye Stress.
1/2019Latanoprost could exacerbate the progression of presbyopia.
11/2018Long-Term Topical Diquafosol Tetrasodium Treatment of Dry Eye Disease Caused by Chronic Graft-Versus-Host Disease: A Retrospective Study.
4/2018The effects of 3% diquafosol sodium eye drop application on meibomian gland and ocular surface alterations in the Cu, Zn-superoxide dismutase-1 (Sod1) knockout mice.
1/2017Suppression of presbyopia progression with pirenoxine eye drops: experiments on rats and non-blinded, randomized clinical trial of efficacy.
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Kazuo Tsubota Research Topics

Disease

127Dry Eye Syndromes (Dry Eye Syndrome)
01/2022 - 08/2002
59Inflammation (Inflammations)
01/2022 - 10/2003
34Cataract (Cataracts)
08/2021 - 08/2002
28Myopia
01/2022 - 11/2004
22Macular Degeneration (Age-Related Maculopathy)
11/2020 - 07/2006
18Choroidal Neovascularization
07/2020 - 10/2006
17Hypoxia (Hypoxemia)
11/2021 - 10/2005
16Diabetic Retinopathy (Retinopathy, Diabetic)
10/2021 - 03/2005
16Keratoconus
10/2021 - 06/2003
16Atrophy
12/2020 - 05/2012
14Wounds and Injuries (Trauma)
01/2021 - 10/2003
13Astigmatism
10/2021 - 11/2004
13Keratitis
09/2020 - 01/2003
12Graft vs Host Disease (Graft-Versus-Host Disease)
09/2021 - 08/2006
12Retinal Degeneration
07/2021 - 07/2006
12Fibrosis (Cirrhosis)
05/2021 - 03/2007
12Bronchiolitis Obliterans Syndrome
04/2021 - 03/2007
11Glaucoma
05/2022 - 01/2008
11Ischemia
08/2021 - 03/2005
11Meibomian Gland Dysfunction
06/2021 - 11/2002
10Uveitis
06/2021 - 08/2005
10Retinal Perforations
01/2021 - 10/2005
9Blindness (Hysterical Blindness)
08/2021 - 01/2011
9Keratoconjunctivitis
11/2014 - 08/2002
7Neoplasms (Cancer)
01/2022 - 10/2003
7Macular Edema
10/2021 - 02/2006
7Allergic Conjunctivitis (Giant Papillary Conjunctivitis)
05/2021 - 05/2004
7Corneal Injuries
12/2017 - 02/2007
7Ulcer
04/2012 - 05/2003
6Open-Angle Glaucoma (Glaucoma, Open Angle)
05/2022 - 06/2006
6Epiretinal Membrane (Epiretinal Membranes)
12/2021 - 02/2006
6Retinal Detachment (Retinal Detachments)
10/2021 - 10/2005
6Presbyopia
01/2021 - 01/2005
6Corneal Edema
01/2021 - 07/2007
6Refractive Errors (Refractive Error)
01/2019 - 05/2002
6Infections
01/2019 - 01/2006
6Corneal Neovascularization
11/2013 - 04/2006
5Retinal Neovascularization
11/2020 - 03/2005
5Limbal Stem Cell Deficiency
10/2020 - 08/2005
5Eye Diseases (Eye Disease)
11/2019 - 01/2010
5Atopic Dermatitis (Atopic Eczema)
06/2015 - 07/2004
4Disease Progression
06/2021 - 01/2002
4Body Weight (Weight, Body)
01/2021 - 10/2016

Drug/Important Bio-Agent (IBA)

64Retinaldehyde (Retinal)IBA
11/2021 - 03/2005
31Ophthalmic Solutions (Eye Drops)IBA
01/2022 - 11/2002
31Fluorescein (Funduscein)FDA LinkGeneric
12/2021 - 06/2003
20Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2021 - 10/2005
19LipidsIBA
01/2021 - 11/2002
13diquafosolIBA
07/2020 - 10/2012
11Rose BengalIBA
01/2021 - 06/2003
10CytokinesIBA
07/2021 - 01/2007
10Proteins (Proteins, Gene)FDA Link
01/2021 - 08/2003
10Therapeutic UsesIBA
01/2020 - 07/2004
9LactoferrinIBA
11/2021 - 08/2003
9Interleukin-6 (Interleukin 6)IBA
03/2019 - 06/2007
9EndotoxinsIBA
01/2016 - 08/2005
9Type 1 Angiotensin ReceptorIBA
01/2013 - 03/2005
8Neuroprotective AgentsIBA
01/2021 - 12/2006
8Oxygen (Dioxygen)IBA
10/2020 - 03/2005
8LuteinIBA
08/2017 - 12/2007
7SteroidsIBA
06/2021 - 10/2003
7Ointments (Pastes)IBA
12/2020 - 07/2004
7Hyaluronic Acid (Hyaluronan)IBA
05/2020 - 03/2005
7AntioxidantsIBA
01/2020 - 03/2009
7MucinsIBA
08/2019 - 10/2005
7Rhodopsin (Visual Purple)IBA
01/2016 - 12/2006
7Lubricant Eye Drops (Artificial Tears)IBA
07/2015 - 04/2004
6Pharmaceutical PreparationsIBA
08/2021 - 01/2011
6Adrenal Cortex Hormones (Corticosteroids)IBA
11/2013 - 05/2009
5Fatty Acids (Saturated Fatty Acids)IBA
01/2022 - 02/2010
5PPAR alphaIBA
10/2021 - 11/2019
5Free RadicalsIBA
10/2020 - 07/2006
5SodiumIBA
07/2020 - 11/2015
5Ranibizumab (Lucentis)FDA Link
05/2020 - 09/2014
5rebamipideIBA
08/2019 - 11/2013
54-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
01/2017 - 01/2015
5ResveratrolIBA
11/2014 - 07/2009
5Messenger RNA (mRNA)IBA
01/2011 - 10/2005
4Eicosapentaenoic AcidIBA
01/2022 - 09/2007
4(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA
10/2021 - 11/2019

Therapy/Procedure

29Laser In Situ Keratomileusis (LASIK)
12/2018 - 01/2002
28Therapeutics
01/2022 - 05/2003
27Lasers (Laser)
07/2020 - 08/2002
26Corneal Transplantation (Keratoplasty)
07/2019 - 04/2003
16Hematopoietic Stem Cell Transplantation
09/2021 - 11/2010
15Vitrectomy
12/2021 - 03/2005
13Transplantation
04/2021 - 03/2002
11Intraocular Lenses (Intraocular Lens)
10/2020 - 10/2005
10Contact Lenses
09/2021 - 09/2004
9Slit Lamp
10/2021 - 07/2004
8Punctal Plugs
10/2015 - 01/2009
7Oral Administration
11/2021 - 01/2014
7Phakic Intraocular Lenses
08/2021 - 05/2005
7Phacoemulsification
06/2015 - 08/2002
6Penetrating Keratoplasty
09/2020 - 08/2006
5Eyeglasses (Spectacles)
11/2021 - 01/2014
5Aftercare (After-Treatment)
06/2021 - 07/2004
4Light Coagulation
10/2021 - 09/2004
4Corneal Cross-Linking
06/2021 - 07/2013
4Anesthesia
01/2021 - 04/2006